Study of Prostatic Lesion for a Period of Five Years

Early detection and management of prostate cancer is an important public health problem in all industrialized countries, where the relative rate of the elderly population is rapidly increasing. Aims of the study is to identify the incidence of the premalignant and malignant conditions and Study of high grade prostatic intraepithelial neoplasia and its association with Prostatic hyperplasia and carcinoma.The present study was undertaken in the Upgraded department of pathology, King George Hospital, Andhra medical college for a period of five years from January 2002 to December 2006. A total of 340 cases evaluated, 277(81.47%) were benign, 11(3.23%) were premalignant and 52 (15.29%) malignant lesions. The ratio of benign to malignant lesions were 5.5: 1 ; Benign prostatic hyperplasia and prostrate carcinoma were the two principal conditions account for majority of all prostrate diseases. Among premalignant lesions only high grade prostatic intraepithelial lesion is seen in association with prostatic carcinoma (40%).